BIOPHYSICS : important questions


BIOPHYSICS

2014
A.      How Gibb’s-Donnan membrane equilibrium regulate the osmotic pressure? Define viscosity. Discuss the factors that contribute to blood viscosity.
B.      Discuss briefly about the glass electrode method of pH-determination.
C.      What is Helmholtz-Guoy double layer? Define zeta potential and explain its significance. Distinguish b/n isotonic and isosmotic solutions.
D.      What is importance of “alkali reserve” of plasma? Define entropy.

2013
E.       Define surface tension. What is significance of Gibbs-Thomson principle in lungs compliance?
F.       Explain, why the living body is consider as a thermodynamic system.
G.     Distinguish b/n dialysis and ultrafiltration. Explain the working principle of acid base indicators.
H.      What is the significance of Henderson-Hasselbalch equation? Describe a suitable method for the determination of osmotic pressure in biological fluids.

2012
I.        Mention the biological significance of diffusion. Distinguish b/n lyophilic and lyophobic colloids?
J.        What do you mean by Gibbs free energy? Define viscosity?
K.      What is ultrafiltration? State its physiological importance.
L.       Show how Gibbs-Donnan membrane equilibrium can influence pH, osmotic pressure and transmembrane potential b/n two sides of semi permeable membrane.

2011
M.    What are Vant Hoff’s laws of osmotic pressure? What do you mean by coagulative properties of a solution?
N.     Discuss the factors that contribute to the blood viscosity?
O.     Discuss about the optical and electrical properties of colloids. Explain the following terms with reference to living system: i) Enthalpy, ii) Entropy.
P.      “The hydrolysis of ɣ- phosphate bond of ATP has a ΔG01 of 7 kcal/mol”-Explain.

2010
Q.     Discuss the biological significance of colloids. Derive Henderson-Hasselbalch equation for buffer system and explain its significance.

R.      What is sol-gel transformation? Define Isoelectric pH. State its importance.

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